Writing Together Online offers structured time to help you spring into writing and stay focused this semester. We offer writing sessions every workday, Monday through Friday. Join our daily 90-minute writing sessions and become part of a community of scholars who connect online, set realistic goals, and write together in the spirit of accountability and camaraderie. The program is open to all MIT students, postdocs, faculty, staff, and affiliates who are working on papers, proposals, thesis/dissertation chapters, application materials, and other writing projects. For more information and to register, go to this link or check the WCC website. Please spread the word and join with colleagues and friends.Register for Spring 2025 Writing Challenge 1Choose those sessions that you want to attend during Challenge 1: February 10th through March 21stMondays 9:00–10:30amTuesdays 8–9:30am and 9:30–11amWednesdays 9:00–10:30amThursdays 8–9:30am and 9:30–11amFridays 8–9:30am and 9:30–11amMIT Students and postdocs who attend at least 5 sessions per challenge will be entered into a raffle of three $25 Amazon gift cards. The raffle will take place on Friday, March 21st. The more you participate, the more times you will be entered into the raffle of prizes.For more information and to register, check the WCC website. Please spread the word and join with peers and friends.The funding support for this program comes from the Office of Graduate Education

Speaker: Alex Lubotzky (Weizmann Institute & the Hebrew University, Simons Distinguished Visiting Professor, MIT)Title: High Dimensional Expanders (HDX) and their applications in pure math and computer scienceAbstract:Expander graphs have been an intensive topic of research in math and CS during the last six decades. In the last two decades a high dimensional theory has emerged with (very different) applications in math & CS.In this series of 8 independent (but related) lectures we present some aspects of the theory of HDX and its applications, a number of open problems and suggestions for further research.A more detailed plan:1. Thursday 2/20/25, 4:30pm, 2-190 (Math Colloquium); refreshments served at 4pm  Introduction: three main problems(a) Gromov overlapping property(b) Locally testable codes(c) Are all groups sofic?2. Tuesday 2/25/25, 4:15-5:15pm, 32-G449 (Theory of Computing Colloquium), refreshments served at 4pmGood Locally testable codes3. Wednesday 2/26/25, 9:30-11am, 2-449Expander graphs: combinatorics, spectral gap, representation theory(Kazhdan property (T), property (\tau) and more) and property testing4. Wednesday 3/5/25, 9:30-11am, 2-449Geometric & topological expanders, Coboundary expanders, Random simplicial complexes and Property testing5. Wednesday 3/12/25, 9:30-11am, 2-449From Ramanujan graphs to Ramanujan complexes6. Wednesday 3/19/25, 9:30-11am, 2-449Stability and group approximation, Garland Theorem and the p-adic Deligne central extensionsWednesday 3/26/25 - Spring vacation7. Wednesday 4/2/26, 9:30-11am, 2-449Some more CS: Agreement tests, direct product test; PCP8. Wednesday 4/9/25, 9:30-11am, 2-449Are there non-sofic groups? The Aldous-Lyons conjecture and more

Sun Ra, Parliament-Funkadelic, George Clinton, Erykah Badu, Octavia E. Butler, Digable Planets, Janelle Monae, Flying Lotus, Grace Jones, Missy Elliott, and moreA new exhibit in Lewis Music Library celebrates the visionary contributions of Afrofuturist artists across various genres and mediums. From the cosmic jazz of Sun Ra and the psychedelic funk of Parliament-Funkadelic and George Clinton, to the neo-soul of Erykah Badu and the sci-fi narratives of Octavia E. Butler, these artists have pushed the boundaries of creativity and imagination.This event is presented as part of Artfinity: A celebration of creativity and community at MIT.

Join a member of our Visitor Experience Team for this 45-minute introductory tour of the MIT Museum. Learn about the collection, our history, and get your questions answered by our gallery experts. Space is limited, please speak to a visitor experience representative at the admission desk when purchasing museum tickets if you would like to participate in the tour.Every Wednesday at 11am Free with museum admission

A martial art known for its many health benefits, tai chi is a moving study in meditation.Designed for small spaces, this class covers fundamental skills including postures, hand, and footwork. A short Yang style tai chi form will be taught.Special clothing is not necessary, but athletic shoes and loose fitting pants are recommended.Registration is required on our wellness class website. If you do not already have an account on this website, you'll need to create one. This is fee-based class and open to the entire MIT community.

Add some pluck to your lunch hour with Big Cypress, the Boston-based Americana quartet defying expectations and breaking genre barriers.While you listen, enjoy a delicious hot cup of soup from Souper Roll Up Cafe (on us, while supplies last!). To keep things sustainable, we encourage you to bring your own mug or bowl. If you do, you’ll get a special sweet treat!

Cultural capital and access to opportunity: Evidence from subcaste norms in India | Paul Novosad

Ten minutes for your mind@2:50 every day at 2:50 pm in multiple time zones:Europa@2:50, EET, Athens, Helsinki (UTC+2) (7:50 am EST) https://us02web.zoom.us/j/88298032734Atlantica@2:50, EST, New York, Toronto (UTC-4) https://us02web.zoom.us/j/85349851047Pacifica@2:50, PST, Los Angeles, Vancouver (UTC=7) (5:50 pm EST) https://us02web.zoom.us/j/85743543699Almost everything works better again if you unplug it for a bit, including your mind. Stop by and unplug. Get the benefits of mindfulness without the fuss.@2:50 meets at the same time every single day for ten minutes of quiet together.No pre-requisite, no registration needed.Visit the website to view all @2:50 time zones each day.at250.org or at250.mit.edu

Date: Wednesday, March 5, 2025 Location: 46-3002 (Singleton Auditorium)Speaker: Haitham Amal, PhD Affiliation: Associate Professor (Tenured), The School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem; Visiting Professor, Boston Children’s Hospital, Harvard Medical School, Harvard UniversityHost: Dr. Alan JasanoffTalk title: The NO Answer for Autism Spectrum DisorderAbstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that shares core behavioral deficits. A few molecular mechanisms have been identified in ASD when most of the studies focus on a single pathway/target. To date, no effective single-drug treatment has been found for ASD, which raises the need for new drug targets. We hypothesize that multi-molecular pathways parallelly may lead to synaptic/neuronal dysfunctions and eventually to ASD phenotype. Our multi-proteomic approach using clinical and mouse model samples identified three novel potential targets possibly orchestrating in ASD: (1) de novo S-nitrosylation (NO-mediated protein modification) of the TSC2 protein. In this talk, I will focus on the role of NO (nitric oxide) in ASD. (2) Upregulation of Gephyrin phosphorylation at specific sites, which affects synaptic plasticity and functions. (3) An abnormal upregulation of the catalytic subunit of the mitochondrial ATP synthase, which may affect the integrity of the inner mitochondrial membrane. Here, we used ASD human plasma samples, human induced pluripotent stem cells (hiPSCs), and mouse models to perform a comprehensive study of the mechanisms underlying ASD pathology. The three-way pathological mechanisms were investigated using a state-of-the-art multi-proteomics platform coupled with sophisticated systems biology analyses to filter out ASD-relevant molecular changes. Pharmacological and CRISPR/Cas9 tools were used to validate the targets and explore the molecular and synaptic features following interventions. Three mouse models of ASD (Shank3, Cntnap2, and Nlgn3) were used to evaluate the behavioral outcomes of the pharmacological treatment. This talk will focus on deciphering unknown multi-way molecular mechanisms underlying ASD pathology that may uncover novel drug targets for ASD.

Please join us on Wednesday, March 5, at 4 pm in Room 2-190 for the C.C. Mei Distinguished Speaker Series with Dr. Trent Northen.Abstract Title: The Chemical Underground: Are Rhizosphere Microbes Hooked on Root Exudates?Abstract:Plants release a large fraction of the carbon they fix into the soil surrounding roots (the rhizosphere), shaping soil microbial communities to support plant health and productivity. Understanding rhizosphere processes is critical for sustainable agriculture and managing soil carbon cycling. However, these interactions remain poorly understood due to the inherent complexity and inaccessibility of these ecosystems. Progress has been further hindered by the lack of standard, replicable experimental systems, making it difficult for scientists to build on each other’s findings.In this talk, I will describe our approach to constructing fabricated rhizosphere ecosystems and share results from the first multilaboratory microbiome reproducibility study. Additionally, I will highlight recent discoveries from our work, including the unexpected exudation of dopamine—a key human neurotransmitter—by plant roots, and discuss the potential role of catecholamines in directing rhizosphere microbial community assembly.Bio:Dr. Trent Northen is Deputy Division Director and a Senior Scientist within the Environmental Genomics and Systems Biology Division at Berkeley Lab. His laboratory focuses on understanding the role of exogenous small molecule metabolites in mediating microbial interactions with other microbes and plant hosts and how these processes impact soil carbon cycling. A long-term goal of the Northen lab is to help harness plants and microbes for sustainable agriculture—including to restore soil carbon and improve soil health. Towards these goals the Northen lab has developed a range of metabolomic, cheminformatic, and bioinformatic capabilities for metabolite identification and analysis. Dr. Northen has also championed the development of fabricated ecosystems spanning scales and complexity.The C.C. Mei Distinguished Speaker Series was founded and has been organized in honor of Prof. Chiang C. Mei. It aims to provide a vibrant forum for highly distinguished speakers, from around the world, to share their research with the CEE, MIT, and local Boston community.

Time: 12:00 PMLocation: Bristol, RI

Every Wednesday night you are invited to come to The Table for peaceful Christian worship in the Chapel at 5:15 pm and dinner in the Main Dining Room of W11 at 6:30 pm.We worship with beautiful songs, open conversation about the Scriptures, prayers and a simple sharing of communion around the altar. Then we enjoy dinner together and good company together. Whether you come every week or just drop by once in a while, there is a caring community for you at the Table.You are truly welcome to come as you are: undergrad, grad, or post-doc; sure of your faith or wondering what it is all about; gay, straight, bi, trans*, questioning. Please join us for no-pressure worship and fellowship.Hosted by the Lutheran Epsicopal Ministry @ MIT. For more information, or to verify gathering times during holiday and vacation periods, please contact chaplains Andrew Heisen (heisen@mit.edu) and Kevin Vetiac (kvet246@mit.edu).

Many people think gentle yoga is too easy and not an effective form of fitness. Think again! You can practice yoga in ways that are both active and gentle at the same time.Come enjoy the many known benefits of yoga through:the practice of active yet gentle, rhythmic movementheld yoga poses and vinyasa flow (moving from pose to pose via the breath)pranayam (breath work)relaxation and meditationIn this well-rounded class, Celeste LeMieux, 500 hr certified Kripalu Yoga Instructor, provides clear instructions and modifications, making it accessible and beneficial to practitioners of all ages and stages of yoga practice and life.You will leave class feeling both stretched and strengthened while also feeling more calm and relaxed. This class is the perfect mid-week reset for body and mind. Come see how less really can be more!Registration is required on our wellness class website. If you do not already have an account on this website, you'll need to create one. This is fee-based class and open to the entire MIT community.

Refuge @ MIT. Join our weekly gathering for Christian students and seekers as we have worship, prayer and Bible study each Wednesday evening. We share some food and enjoy an in depth Bible study, open to all students at MIT.

The MIT wrestling club holds practices in the du Pont Wrestling Room on weeknights 5:30-7pm. All levels of experience welcome! Whether you're looking to learn how to grapple or just want to get in a good workout, wrestling practice is a good time to learn technique, get in some live goes, and have fun with a great group of people.Current schedule is: structured practice MTRF, open mats W, and technique sessions 9-10:30am on Saturday. For more information, contact wrestling-officers@mit.edu.

Curious about the many career options in the healthcare and life sciences fields? Join us for a Speed Networking event featuring MIT alumni who are leaders in fields such as Medical Technology & Devices, Pharmaceuticals, Biomedical Research, AI in Healthcare, Public Health, and practicing Physicians (MD) & Physician-Scientists (MD-PhD).This unique opportunity allows you to engage directly with alumni, ask questions, and gain firsthand insights into their professional journeys. Whether you’re exploring different industries or looking for advice on navigating your next steps, this event provides a great platform to make meaningful connections with our amazing alumni. Attendees will also learn about the opportunities each alumnus can offer – this could include physician shadowing opportunities, micro-internships, full-time internships and jobs, research opportunities and simply opportunities for continued networking.This CAPD event is open to undergraduate and graduate students from all majors and disciplines interested in exploring career paths in Medicine, the Life Sciences, & Healthcare and the different opportunities each alum is promoting.